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Manufacturers of Zetia and Vytorin recently announced that their greatly advertised cholesterol lowering drugs are failing to slow the development of fatty plaque in arterial blood vessels. It showed it might actually promote plaque development. This statement was in the form of a press release not a medical related or professional journal. The press release was very late after the findings in the study were actually discovered.
Why the delay? Maybe because these two drugs had revenue of 5 billion in 2007. The press release was mid 2008 and the findings were available in mid 2007.
This release was the first of some following reports that makes even the uninformed baffled.. Neither of these drugs prevent heart disease however the American Heart Association released their own press release in support of these two drugs. I was perplexed by this and I am sure most men and women would speculate why an association created to prevent heart disease would support expensive drugs that will not work. According to an article in the New York Times it was declared that the American Heart Association gets two million a year from the Merck/Schering-Plough Pharmaceuticals, the group that markets Vytorin. Vytorin by the way is a combination of Zocor and Zetia.
This drug failure and others is spurring doubt about the role of cholesterol in heart disease. Their are many physicians that believe cholesterol has little or nothing to do with heart disease and others who are sure it is a big risk factor. Regardless of which side you agree with, cholesterol is not a cause of heart disease but merely a possible symptom. Vytorin and the other drugs are intended to influence the symptom, not do anything at all for the condition itself. It was announced as far back as 1977 in the American Journal of Epidemiology 105: 281-9 that cholesterol was a very weak indicator at best of heart disease risk. Half of the people who have heart attacks have normal cholesterol.
So what causes heart problems? They are still studying and will continue to do so. At this moment there are a variety of factors including prediabetes and overweight which results from an excess intake of refined sugars, processed sugar like carbohydrates and trans fats. This type of diet elevates blood sugar, insulin and yes cholesterol too.
This is all bad enough but look at these facts.. Our average cholesterol is now lower than in 1960 because everyone has been chewing cholesterol drugs like mad And now two thirds of Americans are heavy which is the number one risk factor for all forms of diabetes and heart problems. Not only that there is more of all forms of diabetes and heart problems now than in 1960 by a wide margin. Cholesterol is not the culprit it is pure and simple a matter of what we eat. And we obviously are eating all the wrong things. The answer is not prescription drugs, the answer is finding natural ways to lower cholesterol.
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